In a way that severely disables, hampers, or damages; to an extent that causes lameness or serious functional limitation.
From cripple + -ing + -ly adverb formation, creating a word describing the manner or degree of crippling effects.
Cripplingly is the adverb form that describes how severely something impacts function—you might say a disease was 'cripplingly expensive' or 'cripplingly restrictive'—showing how the word moved from literal disability to metaphorical limitation.
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