Inflammation or infection of the bladder, renal pelvis, and kidney tissue itself, representing a serious upper urinary tract infection.
From Greek 'kystis' (bladder) + 'pyelos' (pelvis) + 'nephros' (kidney) + 'itis' (inflammation). A compound medical term naming three involved structures.
This is a mouthful because it's describing how a simple bladder infection can escalate up the urinary tract—each prefix tells the story of the infection's journey from bottom to top of the system!
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