A prefix meaning one, single, or alone. As a standalone term, commonly refers to mononucleosis (an infectious disease) or monaural sound reproduction.
From Greek 'monos' meaning alone or single. This productive prefix entered English through Latin and has generated hundreds of words from 'monopoly' to 'monotone', always carrying the sense of singularity or unity.
The prefix 'mono-' is so productive in English that we constantly create new words with it, from 'monogamous' to 'monorail' to 'monotasking'. It's remarkable how a single Greek morpheme continues to help us describe new concepts thousands of years after its origin.
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